Not for IM, intrathecal, IP or SC administration. Avoid in patient w/ history of myasthenia gravis; increased risk of tendinitis & tendon rupture. Discontinue if pain, swelling, inflammation or rupture of tendon occurs; if 1st appearance of skin rash, jaundice or other sign of hypersensitivity; if develop signs & symptoms of hepatitis; if experiences symptoms of neuropathy; if photosensitivity/phototoxicity occurs. Known or suspected CNS disorder that may predispose to seizures or lower seizure threshold.
Clostridium difficile-associated diarrhea may occur; ensure fluid & electrolyte management, protein supplementation, antibiotic treatment of
C. difficile & surgical evaluation if suspected or confirmed. Avoid in patients w/ known QT interval prolongation, uncorrected hypokalemia, receiving class IA (quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmic agents. Carefully monitor blood glucose of diabetics in concomitant use w/ hypoglycemics or insulin. Avoid excessive exposure to sun or UV light. Childn (increased risk of musculoskeletal disorders). Pregnancy & lactation. Elderly.
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